1. General Pathology
    2. 1. The Cell as a Unit of Health and Disease
    2. Cellular Response to Stress and Toxic Insults
    3. Inflammation and Repair
    4. Hemodynamic Disorders, Thromboembolic Disease, and Shock
    5. Genetic Disorders
    6. Diseases of the Immune System
    7. Neoplasia
    8. Infectious Diseases
    9. Environmental and Nutritional Diseases
    10. Diseases of Infancy and Childhood
  2. Systemic Pathology: Diseases of Organ Systems
    3. 11. Blood vessels
    12. The Heart
    13. Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus
    14. Red Blood Cell and Bleeding Disorders
    15. The Lung
    16. Head and Neck
    17. The Gastrointestinal Tract
    18. Liver and Gallbladder
    19. The Pancreas
    20. The Kidney
    21. The Lower Urinary Tract and Male Genital System
    22. The Female Genital Tract
    23. The Breast
    24. The Endocrine System
    25. The Skin
    26. Bones, Joints, and Soft Tissue Tumors
    27. Peripheral Nerves and Skeletal Muscles
    28. The Central Nervous System
    29. The Eye
General Pathology
3. Inflammation and Repair
INFLAMMATION AND REPAIR
Overview of Inflammation: Definitions and General Features
Historical Highlights
Causes of Inflammation
Recognition of Microbes and Damaged Cells
Acute Inflammation
Reactions of Blood Vessels in Acute Inflammation
Changes in Vascular Flow and Caliber
Increased Vascular Permeability (Vascular Leakage)
Responses of Lymphatic Vessels and Lymph Nodes
Leukocyte Recruitment to Sites of Inflammation
Leukocyte Adhesion to Endothelium
Leukocyte Migration Through Endothelium
Chemotaxis of Leukocytes
Phagocytosis and Clearance of the Offending Agent
Phagocytosis
Intracellular Destruction of Microbes and Debris
Neutrophil Extracellular Traps
Leukocyte-Mediated Tissue Injury
Other Functional Responses of Activated Leukocytes
Termination of the Acute Inflammatory Response
Mediators of Inflammation
Vasoactive Amines: Histamine and Serotonin
Arachidonic Acid Metabolites
Cytokines and Chemokines
Complement System
Other Mediators of Inflammation
Morphologic Patterns of Acute Inflammation
Serous Inflammation
Fibrinous Inflammation
Purulent (Suppurative) Inflammation, Abscess
Ulcers
Outcomes of Acute Inflammation
Summary of Acute Inflammation
Chronic Inflammation
Causes of Chronic Inflammation
Morphologic Features
Cells and Mediators of Chronic Inflammation
Role of Macrophages
Role of Lymphocytes
Other Cells in Chronic Inflammation
Granulomatous Inflammation
Systemic Effects of Inflammation
Tissue Repair
Overview of Tissue Repair
Cell and Tissue Regeneration
Cell Proliferation: Signals and Control Mechanisms
Mechanisms of Tissue Regeneration
Repair by Connective Tissue Deposition
Steps in Scar Formation
Angiogenesis
Deposition of Connective Tissue
Remodeling of Connective Tissue
Factors That Influence Tissue Repair
Selected Clinical Examples of Tissue Repair and Fibrosis
Healing of Skin Wounds
Fibrosis in Parenchymal Organs
Abnormalities in Tissue Repair