1. Anatomy
    2. 1. Embryology and Development
    2. Spinal cord and Spinal nerves
    3. Meninges
    4. Cerebrum
    5. Brain stem
    6. Cerebellum
    7. Diencephalon
    8. Cranial Nerves and Related Structures
    9. Ventricular system and CSF flow
    10. Special Sense Organs
  2. Physiology
    3. 11. General Neurophysiology
    12. Brain and Higher Functions
    13. Special Sensory Systems
  3. Pathology
    4. 14. Central Nervous System Disorders
    15. CNS Tumors
    16. Eye Disorders
    17. ENT Disorders
  4. Pharmacology
    5. 18. Introduction to autonomic pharmacology
    19. Cholinergic drugs
    20. Anti-cholinergic drugs
    21. Adrenergic drugs
    22. Anti-adrenergic drugs
    23. Drugs used in Glaucoma
    24. Drugs used in the treatment of pain
    25. Alcohols
    26. Sedative Hypnotics
    27. Antipsychotics
    28. Antianxiety drugs
    29. Antidepressants
    30. Analeptic agents
    31. Local anaesthetics
    32. General anaesthetics
    33. Anti-parkinsonial drugs
    34. Drugs used to reduce appetite or In the treatment of obesity
    35. Drugs for eye diseases
  5. Microbiology
    6. 36. Neisseria meningitidis
    37. Polio virus
    38. Rabies virus
    39. Japanese B Encephalitis Virus
    40. Laboratory Diagnosis of Meningitis
  6. Biochemistry
    7. 41. Introduction
    42. Acetylcholine neurotransmission steps
    43. Snake venom
    44. Neurotransmitters
Microbiology
37. Polio virus

1.

Write short notes on Polio vaccine.

[2064]

➤

2.

List different types of polio vaccine. Write merits and demerits of polio vaccine.

[2064]

➤

3.

Name the clinical material for recovery of polio virus. Describe the method of polio immunization.

[2059, 2058]

➤

4.

Write short note on Polio virus.

[2057]

➤

5.

Describe morphology of polio virus and state how it is transmitted.

[2053]

➤

6.

Discuss pathogenesis of poliovirus.

(5)

[2076]

➤

7.

Write short note:
a. Oral polio vaccine

(2.5)

[2078]

➤

NOMENCLATURE
family
Picornaviridae
genus
Enterovirus
MORPHOLOGY
image
    ◈ data:
    ■ attributes:
    ● url: https://upload.wikimedia.org/wikipedia/commons/a/ac/Polio_virus.png
size
  1. small
  2. 20-30 nm diameters
genetic_material
Single stranded RNA (positive sense)
envelope
Non-enveloped
symmetry
60 capsomeres contain 4 viral protein (VP1-VP4)
viral_protein
VP1 carries the major antigenic site
TYPES
based_on_neutralization_test
type_1
Most epidemics of paralytic poliomyelitis
type_2
Most common vaccine derived poliovirus (VDPV) isolates
type_3
Most common serotypes to cause vaccine associated paralytic poliomyelitis (VAPP)
PATHOGENESIS
source_of_infection
Faeces of patient and carrier
mode_of_transmission
Faeco-oral route
incubation_period
9-12 days
mermaid
    VACCINE
    table